All You Need to Know About the History of Cannabinoids

The use of cannabis has been prohibited by the international community for a long time. Many argued that the reason for its prohibition was lack of evidence about its benefits. The recent discovery of the therapeutic benefits is far from the real truth. The first documented practice of cannabis dates back to 2737 BC.

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Evolution of CBD

The first known documented use of cannabis was in 2737 BC by Chinese Emperor Sheng Nung. He used to drink cannabis-infused tea to relieve symptoms of various diseases such as malaria, gout, rheumatism, and increase memory.

Queen Victoria was believed to have used CBD to reduce the pain of period cramps during her reign that ended in 1901. Even with documented evidence of the use of CBD as a therapeutic resource, it was prohibited as a medicine due to a lack of scientific evidence.

In the year 1839 AD, William B. O’Shaughnessy, an Irish medical researcher, and physician had published a study investigating the therapeutic effects of the cannabis plant.

This began medical research on the effects of the plant. The study suggested the use of cannabis as an anesthetic and although the study was controversial, it opened the door to more research on cannabis.

 Discovery of cannabinoids

The discovery of cannabinoid started in a century after the study of O’Shaughnessy. Robert S. Cahn, a British chemist published a partial structure of Cannabinol and later published a fully formed structure in 1940.

In the year 1942, an American chemist named Roger Adams created history when he isolated the first cannabinoid and named it Cannabidiol or CBD. He also discovered the psychoactive and intoxicating compound named Tetrahydrocannabidiol or THC.

Early research of cannabinoid pharmacy

The first discovery of individual cannabinoids was made in 1963 which aided to the discovery between CBD and euphoria a year later. After the discovery of the stereochemistry of CBD and THC, it was revealed that CBD is not a mind-altering compound and does not have euphoric effects. It was also discovered that THC does cause euphoria.

In the 1980s there were studies of CBD being used for the treatment of epilepsy. Even though the research showed positive results in half of the patients, it was not considered a breakthrough as there were many stigmas surrounding cannabis.


The information above shows the evolution of CBD. The state of California legalized marijuana in 1996 and slowly people began understanding the therapeutic benefits of CBD. Now the FBA-approved CBD products have been legalized and sold freely by medical and cosmetic companies.

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